Pharmacology Primer
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portes grátis
Pharmacology Primer
Techniques for More Effective and Strategic Drug Discovery
Kenakin, Terry P.
Elsevier Science & Technology
08/2022
502
Mole
Inglês
9780323992893
15 a 20 dias
450
Descrição não disponível.
1. What is Pharmacology?
2. How Different Tissues Process Drug Response
3. Drug-Receptor Theory
4. Pharmacological Assay Formats: Binding
5. Drug Targets and Drug-Target Molecules
6. Agonists: The Measurement of Affinity and Efficacy in Functional Assays
7. Orthosteric Drug Antagonism
8. Allosteric Modulation
9. The Optimal Design of Pharmacological Experiments
10. Pharmacokinetics
11. Safety Pharmacology
12. The Drug Discovery Process
13. Selected Pharmacological Methods
2. How Different Tissues Process Drug Response
3. Drug-Receptor Theory
4. Pharmacological Assay Formats: Binding
5. Drug Targets and Drug-Target Molecules
6. Agonists: The Measurement of Affinity and Efficacy in Functional Assays
7. Orthosteric Drug Antagonism
8. Allosteric Modulation
9. The Optimal Design of Pharmacological Experiments
10. Pharmacokinetics
11. Safety Pharmacology
12. The Drug Discovery Process
13. Selected Pharmacological Methods
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Affinity; Agonist assays; Allosteric models; Allosteric protein interactions; Biologics; Cellular signaling; Classical receptor theory; Competitive antagonism; Data fitting; Displacement binding; Distribution; Dose-response curves; Drug absorption; Drug affinity; Drug antagonism; Drug receptors; Drug targets; Efficacy; Enzymes; Excretion; Experimental design; Full agonists; Functional receptor activity; Ion channels; Metabolism; Molecular dynamics; Negative and positive allosterism; Noncompetitive antagonism; Nuclear receptors; Null methods; Operation model; Operational model; Partial agonists; Pharmacological assays; Pharmacological models; Pharmacology; Predicting agonism; Receptor binding; Receptors; Saturation binding; Small molecule drug ligands; Target coverage; Ternary complex model
1. What is Pharmacology?
2. How Different Tissues Process Drug Response
3. Drug-Receptor Theory
4. Pharmacological Assay Formats: Binding
5. Drug Targets and Drug-Target Molecules
6. Agonists: The Measurement of Affinity and Efficacy in Functional Assays
7. Orthosteric Drug Antagonism
8. Allosteric Modulation
9. The Optimal Design of Pharmacological Experiments
10. Pharmacokinetics
11. Safety Pharmacology
12. The Drug Discovery Process
13. Selected Pharmacological Methods
2. How Different Tissues Process Drug Response
3. Drug-Receptor Theory
4. Pharmacological Assay Formats: Binding
5. Drug Targets and Drug-Target Molecules
6. Agonists: The Measurement of Affinity and Efficacy in Functional Assays
7. Orthosteric Drug Antagonism
8. Allosteric Modulation
9. The Optimal Design of Pharmacological Experiments
10. Pharmacokinetics
11. Safety Pharmacology
12. The Drug Discovery Process
13. Selected Pharmacological Methods
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Affinity; Agonist assays; Allosteric models; Allosteric protein interactions; Biologics; Cellular signaling; Classical receptor theory; Competitive antagonism; Data fitting; Displacement binding; Distribution; Dose-response curves; Drug absorption; Drug affinity; Drug antagonism; Drug receptors; Drug targets; Efficacy; Enzymes; Excretion; Experimental design; Full agonists; Functional receptor activity; Ion channels; Metabolism; Molecular dynamics; Negative and positive allosterism; Noncompetitive antagonism; Nuclear receptors; Null methods; Operation model; Operational model; Partial agonists; Pharmacological assays; Pharmacological models; Pharmacology; Predicting agonism; Receptor binding; Receptors; Saturation binding; Small molecule drug ligands; Target coverage; Ternary complex model
