Biomedical Applications of Functionalized Nanomaterials
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Biomedical Applications of Functionalized Nanomaterials
Concepts, Development and Clinical Translation
Das Neves, Jose (Post-Doctoral Researcher at INEB, the Instituto de Engenharia Biomedica, Porto, Portugal); Sarmento, Bruno (Affiliated Investigator, INEB-Instituto de Engenharia Biomedica, University of Porto, Portugal and Assistant Professor, Pharmaceutical Technology, Department of Pharmaceutical Sciences, ISCS-N, Gandra, Portugal)
Elsevier - Health Sciences Division
03/2018
778
Mole
Inglês
9780323508780
15 a 20 dias
Descrição não disponível.
Introduction: From the "magic bullet" to advanced nanomaterials: An historical perspective Part I. Ligand selection and functionalization of nanomaterials 1. Phage display technology for screening antibody fragments 2. Bioengineered approaches for site-orientation of peptide-based ligands of nanomaterials 3. Engineered protein variants for bioconjugation 4. Engineering of nanozymes for biomedical applications 5. Strategies for the functionalization of mesoporous nanomaterials for biomedical use 6. Systematic evolution of ligands by exponential enrichment (SELEX) for aptamer selection 7. Biological methodologies for assessment of functionality of nanomaterials Part II. Specific applications of functionalized nanomaterials in therapy and diagnostics 8. Functionalized graphene-based materials for bioimaging applications 9. Multifunctional magnetic nanoparticles for theranostic applications 10. Stimuli-sensitive grafting polymers for targeted anticancer drug delivery 11. Functional moieties for intracellular traffic of nanomaterials 12. Biofunctionalized mesoporous silica nanomaterials for nuclei targeting 13. Lipid-derived nanoparticles for targeted delivery of siRNA 14. Aptamer-siRNA nanoparticles for targeted anti-HIV therapeutics 15. Peptide and protein self-assembled nanofibers for vaccine development and immunotherapy 16. Functional biomaterials for vascular tissue engineering 17. Functionalized hydrogels for culture and delivery of cells Part III. Manufacturing, regulatory challenges and clinical testing of functionalized nanomaterial-based products 18. Manufacturing and safety guidelines for the manufactured functional nanomaterials 19. Challenges for planning clinical trials of functionalized nanomaterials 20. Clinical testing of ACCURINS (R) therapeutics: challenges and lessons learned
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Introduction: From the "magic bullet" to advanced nanomaterials: An historical perspective Part I. Ligand selection and functionalization of nanomaterials 1. Phage display technology for screening antibody fragments 2. Bioengineered approaches for site-orientation of peptide-based ligands of nanomaterials 3. Engineered protein variants for bioconjugation 4. Engineering of nanozymes for biomedical applications 5. Strategies for the functionalization of mesoporous nanomaterials for biomedical use 6. Systematic evolution of ligands by exponential enrichment (SELEX) for aptamer selection 7. Biological methodologies for assessment of functionality of nanomaterials Part II. Specific applications of functionalized nanomaterials in therapy and diagnostics 8. Functionalized graphene-based materials for bioimaging applications 9. Multifunctional magnetic nanoparticles for theranostic applications 10. Stimuli-sensitive grafting polymers for targeted anticancer drug delivery 11. Functional moieties for intracellular traffic of nanomaterials 12. Biofunctionalized mesoporous silica nanomaterials for nuclei targeting 13. Lipid-derived nanoparticles for targeted delivery of siRNA 14. Aptamer-siRNA nanoparticles for targeted anti-HIV therapeutics 15. Peptide and protein self-assembled nanofibers for vaccine development and immunotherapy 16. Functional biomaterials for vascular tissue engineering 17. Functionalized hydrogels for culture and delivery of cells Part III. Manufacturing, regulatory challenges and clinical testing of functionalized nanomaterial-based products 18. Manufacturing and safety guidelines for the manufactured functional nanomaterials 19. Challenges for planning clinical trials of functionalized nanomaterials 20. Clinical testing of ACCURINS (R) therapeutics: challenges and lessons learned
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
