Feldman and Pike's Vitamin D

Feldman and Pike's Vitamin D

Volume One: Biochemistry, Physiology and Diagnostics

Giovannucci, Edward; Bouillon, Roger; Hewison, Martin; Goltzman, David; Meyer B., Mark; Welsh, JoEllen

Elsevier Science & Technology

03/2024

1230

Dura

Inglês

9780323913867

15 a 20 dias

Descrição não disponível.
1. Book introduction: Major trends in vitamin D research;
2. Evolution of human skin pigmentation and vitamin D;
3. Photobiology of vitamin D;
4. The activating enzymes of vitamin D metabolism (25- and 1a-hydroxylases);
5. CYP24A1: structure, function, and physiological role;
6. Alternative pathways for vitamin D metabolism;
7. Vitamin Debinding protein;
8. Regulation of renal vitamin D metabolism;
9. Regulation of extra-renal synthesis of 1,25(OH)2D;
10. Structural basis for ligand activity in vitamin D receptor;
11. Genome-wide perspectives on vitamin D receptor actions;
12. Vitamin D, chromatin, and epigenetics;
13. The diverse genomic mechanisms of action of the vitamin D receptor;
14. Vitamin D and microRNAs;
15. Pathway based-analysis of transcriptomic data from vitamin D studies
16. Vitamin D and the kidney;
17. Vitamin D and the calcium-sensing receptor;
18. Regulation of intestinal calcium and phosphate absorption by vitamin D;
19. Vitamin D and FGF23;
20. Osteoclastogenesis and vitamin D;
21. Vitamin D activity in osteoblasts and osteocytes;
22. Cartilage;
23. Vitamin D and bone: an integrated approach;
24. Vitamin D in dentoalveolar and oral health;
25. Role of vitamin D in skin and hair biology;
26. Vitamin D and the cardiovascular system;
27. Vitamin D, brain development and function;
28. Vitamin D, VDR, and adipose tissue: focus on cellular mechanisms;
29. Vitamin D and skeletal muscle;
30. Understanding vitamin D from mouse knockout models;
31. Pharmacology and pharmacokinetics of vitamin D;
32. Vitamin D as a modifier of genomic function and phenotypic expression during pregnancy;
33. The role of vitamin D physiology in regulating calcium and bone metabolism in mother and child: pregnancy, lactation, postweaning, fetus, and neonate;
34. Vitamin D and the placenta;
35. Consequences of perinatal vitamin D deficiency on later bone health;
36. Adolescence and acquisition of peak bone mass;
37. The role of vitamin D in orthopedic surgery;
38. Vitamin D and muscle performance in athletes and older adults;
39. Role in reproductive biology and dysfunction in women;
40. Vitamin D, reproductive endocrinology, and male reproductive organ function in health and disease;
41. Vitamin D and the renineangiotensin system;
42. Vitamin D: presence and function in the eye;
43. Adult vitamin D deficiency and adverse brain outcomes
44. Vitamin D and the lung;
45. Design and synthesis of vitamin D analogs;
46. Structure function relationships of VDR ligands;
47. Modulating vitamin D receptore coregulator binding with small molecules;
48. Mass spectrometry assays of vitamin D metabolites;
49. Measurement and quality assessment of total and free 25-hydroxyvitamin D;
50. Vitamin D tissue distribution by mass spectrometry imaging;
Index for Volume 1
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Vitamin D; vitamin D receptor; vitamin D metabolism; vitamin D deficiency; 25-hydroxyvitamin D3; 1,25-Dihydroxyvitamin D; 1a-Hydroxylase; vitamin D status; sun exposure; vitamin D fortification; vitamin D supplementation; bone health; osteoporosis; organ transplantation, diabetes mellitus; obesity; metabolic syndrome; cancer; antibacterial immunity; antiviral immunity; vitamin D and diseases