Medical Applications of Mass Spectrometry

Medical Applications of Mass Spectrometry

Vertes, Akos (W.M. Keck Institute for Proteomics Technology & Applications, Washington DC, U.S.A.); Vekey, Karoly (Chemical Research Center, Hungarian Academy of Sciences, Budapest, Hungary); Telekes, Andreas (National Oncology Institute, Budapest, Hungary)

Elsevier Science & Technology

10/2007

606

Dura

Inglês

9780444519801

15 a 20 dias

Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. This book addresses the key issues in the medical applications of mass spectrometry at the level for the intended readership.
1. Introduction 2. Basics of analytical chemistry and mass spectrometry for medical professionals 3. Ethical, legal, safety and scientific aspects of medical research 4. Biomedical sampling 5. Separation methods 6. Mass spectrometry instrumentation and techniques 7. Cheminformatics: multivariate mathematical-statistical methods for data evaluation 8. Mass spectrometry in proteomics 9. De novo sequencing of peptides 10. Protein bioinformatics 11. Analysis of complex lipidomes 12. Medical laboratory practice - possibilities for mass spectrometry 13. Therapeutic drug monitoring 14. Mass spectrometry of infectious pathogens 15. Proteomics of viruses and their host partners 16. Neonatal diagnostics 17. Application of mass spectrometry in oncology 18 Application of mass spectrometry in brain research: neurotransmitters, neuropeptides and brain proteins 19. The human pituitary proteome: clinical applications 20. Mass spectrometry of proteinous allergens inducing human diseases 21. Mass spectrometry in clinical treatment 22. Biomarker discovery 23. Molecular imaging by mass spectrometry 24. Brief outlook
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