Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics

Section I: Physico-chemical aspects of dosage forms 1. Physico-chemical factors influencing drug degradation 2. Stability and accelerated stability studies of dosage forms 3. Solubility of drugs 4. Drug dissolution studies of pharmaceutical formulations 5. Pharmaceutical granulation: Engineering perspective and futuristic trends 6. Tablet compression and consolidation: Theory and applications Section II: Biopharmaceutics 7. Introduction to Biopharmaceutics 8. Gastrointestinal absorption of drugs 9. Routes of drug administration and their impact in biopharmaceutics 10. Drug elimination and renal excretion of drugs 11. Membrane transport and permeation of drugs 12. Factors affecting drug absorption and disposition 13. Bioavailability and bioequivalence 14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy 15. Dosage regimen 16. Basic pharmacokinetics and compartment modeling 17. Multicompartment models 18. Nonlinear pharmacokinetics 19. Computer-aided biopharmaceutical model development 20. Computer simulations in pharmacokinetics 21. WHO and ICH Guidelines for 'Good Manufacturing Practices' 22. Pilot plant scale up techniques in pharmaceutical product development 23. Advances in solid dosage forms

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• Farmacologia
• Medicina pré-clínica: ciências básicas
• Biotecnologia

Drug discovery; drug development; membrane transport; bioavailability; bioequivalence; solubility; dosage; stability