Precision Medicine in Neurodegenerative Disorders
Precision Medicine in Neurodegenerative Disorders
Part I
Espay, Alberto J.
Elsevier - Health Sciences Division
06/2023
288
Dura
Inglês
9780323855389
15 a 20 dias
Part 2 Pitfalls in Definitions, Cohorts, and Measures of Progression 10. Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration 11. The theoretical problems of "prodrome? and "phenoconversion? in neurodegeneration 12. The dilemma between milestones of progression vs. clinical scales in Parkinson disease 13. Biomarkers of diagnosis, prognosis, pathogenesis, response to therapy: Convergence or divergence? Lessons from Alzheimer Disease and synucleinopathies 14. Challenges in the study of individuals at risk for Parkinson disease 15. The challenging quest of neuroimaging: From clinical to molecular-based subtyping of Parkinson disease and atypical parkinsonisms
Part 2 Pitfalls in Definitions, Cohorts, and Measures of Progression 10. Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration 11. The theoretical problems of "prodrome? and "phenoconversion? in neurodegeneration 12. The dilemma between milestones of progression vs. clinical scales in Parkinson disease 13. Biomarkers of diagnosis, prognosis, pathogenesis, response to therapy: Convergence or divergence? Lessons from Alzheimer Disease and synucleinopathies 14. Challenges in the study of individuals at risk for Parkinson disease 15. The challenging quest of neuroimaging: From clinical to molecular-based subtyping of Parkinson disease and atypical parkinsonisms