Protein Design and Structure

Protein Design and Structure

Donev, Rossen

Elsevier Science & Technology

04/2022

432

Dura

Inglês

9780323992299

15 a 20 dias

840

Descrição não disponível.
1. Algorithms for protein design
Sekhar Talluri
2. Computational prediction of protein functional sites-Applications in biotechnology and biomedicine
Florencio Pazos
3. Structure and chemistry of enzymatic active sites that play a role in the switch and conformation mechanism
Chandrabose Selvaraj, Ondipilliraja Rudhra, Abdulaziz S. Alothaim, Mustfa Alkhanani, and Sanjeev Kumar Singh
4. Accelerating therapeutic protein design
Mohammad ElGamacy
5. Aromatic interactions directing peptide nano-assembly
Sajitha Sasidharan and Vibin Ramakrishnan
6. Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
Jose C. Martinez, Francisco Castillo, Javier Ruiz-Sanz, Javier Murciano-Calles, Ana Camara-Artigas, and Irene Luque
7. The structural basis of histone modifying enzyme specificity and promiscuity: Implications for metabolic regulation and drug design
Tim J. Kamerzell, Brittney Mikell, Lei Chen, Harold Elias, Buddhadeb Dawn, Calum MacRae, and C. Russell Middaugh
8. Designing synthetic transcription factors: A structural perspective
Aparna Boral, Madhurima Khamaru, and Devrani Mitra
9. Recent advances in structural studies of 14-3-3 protein complexes
Nikolai N. Sluchanko
10. Immunosafe(r)-by-design nanoparticles: Molecular targets and cell signaling pathways in a next-generation model proxy for humans
Annalisa Pinsino and Maria Di Bernardo
11. Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach
S. Udhaya Kumar, Balu Kamaraj, Rinku Polachirakkal Varghese, V. Anu Preethi, R. Bithia, and C. George Priya Doss
12. Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface
D. Thirumal Kumar, S. Udhaya Kumar, Nikita Jain, Baviri Sowmya, Kamakshi Balsekar, R. Siva, Balu Kamaraj, Mariem Sidenna, C. George Priya Doss, and Hatem Zayed
13. Evolutionary aspect of Miltefosine transporter proteins in Leishmania major
Ritika Kabra and Shailza Singh
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A* algorithm; Active site; Aromatic interactions; Basic leucine zipper; Binding affinity; Biological circuits; Branch-and-bound algorithm; BRCA1-BARD1; Clinical optimization; Cofactor; Computational protein design; Conformational search; Conserved position; Cryoelectron microscopy; De novo protein design; Design speed and accuracy; Drug design; Enzyme chemistry; EVH1 domains; Evolutionary algorithms; Evolutionary divergence; Fasting blood glucose; G6PC2; Gibbs free energy landscape; GYF domains; Helix-turn-helix; Histone-modifying enzyme; Homeodomain; Immune-nanoparticle recognition and interaction in vitro; Interaction networks; Intracellular signaling; Leishmania major; Ligand design; Machine learning; Membrane simulation; Metabolism; Molecular dynamics; Multiple sequence alignment; Mutations; Nanoparticle surface functionalization for biomedical use; Nanostructures; Neural networks; P. lividus immune cells; P. lividus physiological coelomic fluid (blood equivalent); Pathogenicity; Peptides; Phosphorylation; Phylogenetic analysis; Polyproline peptides; Protein complexes; Protein design; Protein design algorithms; Protein efficiency; Protein engineering; Protein function; Protein functional site; Protein structure; Protein-protein interaction; Protein-protein interactions; Quantum computing; Reaction mechanism; Sea urchin protein "corona?; Sea urchin-based nanoparticles; Secretome; Self-assembly; SH3 domains; Specificity determining position; Stability; Structural biology; Structural changes; Structure; Structure/function relationships in protein domains; Supramolecular chemistry; Synthetic transcription factor; Therapeutic proteins; Transporter proteins; Type-2 diabetes; UEV domains; Virtual screening; WW domains; X-Ray crystallography; Zinc finger