Fatty Acid-Binding Proteins and Their Roles in Human Health and Disease

Section 1: Overview of FABP biology 1. Introduction to FABP family, tissue expression & ligand specificity 2. FABP expression and regulation, structure homology with other proteins 3. Structure and functions of FABPs and other similar proteins such as SCP2, and alpha-synuclein 4. FABPs in cell signaling, angiogenesis, and gene expression 5. FABPs in cardiac remodeling 6. Impacts of dietary lipids on FABPs and cell growth 7. FABP and endocannabinoid metabolism in the liver and brain Section 2: FABPs and inflammation 8. FABPs in inflammatory diseases 9. FABPs in immune cell functions 10. Roles of FABPs in brain inflammation 11. FABP in adipose tissue inflammation Section-3: FABPs in metabolic disorders & Obesity 12. FABPs in the development of insulin resistance and diabetes 13. FABPs in the development and progression of cardiovascular diseases 14. FABPs and metabolic syndrome 15. Role of FABPs in obesity Section-4: FABPs and human diseases 16. FABPs dysregulation and human diseases 17. FABPs and brain diseases 18. FABPs and liver diseases 19. FABPs and developmental diseases 20. FABPs in reperfusion injury in tissues 21. FABPs in celiac diseases Section 5: FABPs and Cancers 21. Diverse roles of FABPs in the development of cancers 22. FABPs in Prostate, bladder and kidney cancers 23. Capter-24: FABPs in psoriasis 24. FABPs and breast cancers Section 6: FABPs in Clinical applications 25. Plasma FABPs as biomarkers of diseases 26. Clinical usefulness of urinary FABPs in assessing several diseases 27. FABPs as therapeutic targets in different diseases

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• Biologia Celular (citologia)

<p>Fatty acid-binding proteins; FABPs; free fatty acids; FABP biology; FABPs and health; FABPs and diseases; cell signaling; lipid trafficking; lipid metabolism; biomarkers</p>